Authors Detail

Sorwe Mojtahed Poor, Thomas Ulshöfer, Laureen Gabriel, Marina Henke, Michaela Köhm, Frank Behrens, Gerd Geisslinger, Michael J. Parnham, Harald Burkhardt, Susanne Schiffmann

Immunogenicity assay development and validation for biologic therapy as exemplified by ustekinumab

2019, Clinical & Experimental Immunology

Leonard Blum, Nadja Tafferner, Ilknur Spring, Jennifer Kurz, Natasja de Bruin, Gerd Geisslinger, Michael J. Parnham, Susanne Schiffmann

Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression.

2018, Journal of Molecular Medicine

Leonard Blum, Susanne Schiffmann, Michael J. Parnham

Immunomodulation by antibiotics

2018, Fighting Antimicrobial Resistance (IAPC Book)

Hiromi Shiratori, Carmen Feinweber, Sonja Luckhardt, Nadja Wallner, Gerd Geisslinger, Andreas Weigert, Michael J. Parnham

An in vitro test system for compounds that modulate human inflammatory macrophage polarization

2018, European Journal of Pharmacology

Sandra Vomund, Anne Schäfer, Michael J. Parnham, Bernhard Brüne, Andreas von Knethen

Nrf2, the Master Regulator of Anti-Oxidative Responses

2017, International Journal of Molecular Sciences

Jessica Roos, Marcus Peters, Isabelle Maucher, Benjamin Kühn, Jasmin Fettel, Nadine Hellmuth, Camilla Brat, Benita Sommer, Anja Urbschat, Matthias Piesche, Anja Vogel, Eugen Proschak, Rene Blöcher, Estel la Buscato, Ann-Kathrin Häfner, Carmela Matrone, Oliver Werz, Juliana Heidler, Ilka Wittig, Carlo Angioni, Gerd Geisslinger, Michael J. Parnham, Kai Zacharowski, Dieter Steinhilber, Thorsten Maier

Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy

2017, Antioxidants & Redox Signaling

Hiromi Shiratori, Carmen Feinweber, Sonja Luckhardt, Bona Linke, Eduard Resch, Gerd Geisslinger, Andreas Weigert, Michael J. Parnham

THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro

2017, Molecular Immunology

Hiromi Shiratori, Carmen Feinweber, Claudia Knothe, Jörn Lötsch, Dominique Thomas, Gerd Geisslinger, Michael J. Parnham, Eduard Resch

High-Throughput Analysis of Global DNA Methylation Using Methyl-Sensitive Digestion

2016, PloS one

Marco Sisignano, Carlo Angioni, Chul-Kyu Park, Sascha Meyer Dos Santos, Holger Jordan, Maria Kuzikov, Di Liu, Sebastian Zinn, Stephan Hohmann, Yannick Schreiber, Béla Zimmer, Mike Schmidt, Ruirui Lu, Jing Suo, Dong-Dong Zhang, Stephan M. G. Schäfer, Martine Hofmann, Ajay S. Yekkirala, Natasja de Bruin, Michael J. Parnham, Clifford J. Woolf, Ru-Rong Ji, Klaus Scholich, Gerd Geisslinger

Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain

2016, Proceedings of the National Academy of Sciences

Marco Brenneis, Ramin Aghajaanpour, Tilo Knape, Lisa Sha, Holger Neb, Patrick Meybohm, Kai Zacharowski, Ingeborg Hauser, Stefan Büttner, Michael J. Parnham, Bernhard Brüne, Andreas von Knethen

Pparγ Expression in T Cells as a Prognostic Marker of Sepsis

2016, Shock

Susanne Beyer, Li Xie, Mike Schmidt, Natasja de Bruin, Mukul Ashtikar, Sabrina Ruschenbaum, Christian Lange, Vitali Vogel, Werner Mantele, Michael J. Parnham, Matthias G. Wacker

Optimizing novel implant formulations for the prolonged release of biopharmaceuticals using in vitro and in vivo imaging techniques

2016, Journal of Controlled Release

Julia Barthelmes, Nadja Tafferner, Jennifer Kurz, Natasja de Bruin, Michael J. Parnham, Gerd Geisslinger, Susanne Schiffmann

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues

2016, Journal of visualized experiments

Natasja de Bruin, Katja Schmitz, Susanne Schiffmann, Nadja Tafferner, Mike Schmidt, Holger Jordan, Annett Haussler, Irmgard Tegeder, Gerd Geisslinger, Michael J. Parnham

Multiple rodent models and behavioral measures reveal unexpected responses to FTY720 and DMF in experimental autoimmune encephalomyelitis

2016, Behavioural brain research

Isabelle Maucher, Michael Rühl, Simon Kretschmer, Bettina Hofmann, Benjamin Kühn, Jasmin Fettel, Anja Vogel, Karsten T. Flügel, Georg Manolikakes, Nadine Hellmuth, Ann-Kathrin Häfner, Vahid Golghalyani, Ann-Katrin Ball, Matthias Piesche, Carmela Matrone, Gerd Geisslinger, Michael J. Parnham, Michael Karas, Dieter Steinhilber, Jessica Roos, Thorsten Maier

Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418

2016, Biochemical Pharmacology

Nadja Tafferner, Julia Barthelmes, Max Eberle, Thomas Ulshöfer, Marina Henke, Natasja de Bruin, Christoph Mayer, Christian Förch, Gerd Geisslinger, Michael J. Parnham, Susanne Schiffmann

Alpha-methylacyl-CoA racemase deletion has mutually counteracting effects on T-cell responses, associated with unchanged course of EAE

2016, European journal of immunology

Jessica Roos, Sabine Grösch, Oliver Werz, Peter Schröder, Slava Ziegler, Simone Fulda, Patrick Paulus, Anja Urbschat, Benjamin Kühn, Isabelle Maucher, Jasmin Fettel, Thomas Vorup-Jensen, Matthias Piesche, Carmela Matrone, Dieter Steinhilber, Michael J. Parnham, Thorsten Maier

Regulation of tumorigenic Wnt signaling by cyclooxygenase-2, 5-lipoxygenase and their pharmacological inhibitors: A basis for novel drugs targeting cancer cells?

2016, Pharmacology & therapeutics

Christoph Lehmann, Julia Homann, Ann-Katrin Ball, Rene Blöcher, Thea K Kleinschmidt, Devaraj Basavarajappa, Nerea Ferreiros, Ann-Kathrin Häfner, Olof Radmark, Jesper Z Haeggstrom, Gerd Geisslinger, Michael J. Parnham, Dieter Steinhilber, Astrid Stefanie Kahnt

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein

2015, FASEB Journal

Susanne Beyer, Aline Moosmann, Astrid Stefanie Kahnt, Thomas Ulshöfer, Michael J. Parnham, Nerea Ferreiros, Sylvia Wagner, Matthias G. Wacker

Drug Release and Targeting: the Versatility of Polymethacrylate Nanoparticles for Peroral Administration Revealed by Using an Optimized In Vitro-Toolbox

2015, Pharmaceutical research

Carmen Walter, Violeta Dimova, Julia Bu, Michael J. Parnham, Bruno Oertel, Jörn Lötsch

Inverted Perceptual Judgment of Nociceptive Stimuli at Threshold Level following Inconsistent Cues

2015, PLoS One

Christoph Mayer, Nadja Tafferner, Julia Barthelmes, Max Eberle, Nerea Ferreiros, Thomas Ulshöfer, Marina Henke, Natasja de Bruin, Gerd Geisslinger, Christian Förch, Michael J. Parnham, Susanne Schiffmann

Different pathophysiological relevance of branched fatty acid metabolism in mice and men: alpha-methylacyl-CoA racemase regulates the T cell response only in experimental autoimmune encephalomyelitis but not in multiple sclerosis

2015, Multiple Sclerosis Journal

Tilo Knape, Daniel Flesch, Laura Kuchler, Lisa Sha, Annika K Giegerich, Sandra Labocha, Mario Wurglics, Manfred Schubert-Zsilavecz, Eugen Proschak, Bernhard Brüne, Michael J. Parnham, Andreas von Knethen

Identification and characterisation of a prototype for a new class of competitive PPARgamma antagonists

2015, European journal of pharmacology

Katja Schmitz, Natasja de Bruin, Philipp Bishay, Julia Barthelmes, Annett Haussler, Christine Altmann, Nerea Ferreiros, Jörn Lötsch, Alfred Ultsch, Michael J. Parnham, Gerd Geisslinger, Irmgard Tegeder

R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice

2014, EMBO molecular medicine

Julia Homann, Christoph Lehmann, Astrid Stefanie Kahnt, Dieter Steinhilber, Michael J. Parnham, Gerd Geisslinger, Nerea Ferreiros

Chiral chromatography-tandem mass spectrometry applied to the determination of pro-resolving lipid mediators

2014, Journal of Chromatography A

Prof. Dr. Michael J. Parnham

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