Authors Detail

Contact Info

Translational Medicine & Pharmacology TMP
Fraunhofer Institute for Molecular Biology and Applied Ecology IME

E-Mail: tafferner@trip-gradschool.de

Project:
The role of AMACR in the development of multiple sclerosis

Supervisor:
Prof. Dr. Michael Parnham

Project period: 2013 - 2016

Published Papers

Leonard Blum, Nadja Tafferner, Ilknur Spring, Jennifer Kurz, Natasja de Bruin, Gerd Geisslinger, Michael J. Parnham, Susanne Schiffmann

Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression.

2018, Journal of Molecular Medicine

Julia Barthelmes, Nadja Tafferner, Jennifer Kurz, Natasja de Bruin, Michael J. Parnham, Gerd Geisslinger, Susanne Schiffmann

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues

2016, Journal of visualized experiments

Natasja de Bruin, Katja Schmitz, Susanne Schiffmann, Nadja Tafferner, Mike Schmidt, Holger Jordan, Annett Haussler, Irmgard Tegeder, Gerd Geisslinger, Michael J. Parnham

Multiple rodent models and behavioral measures reveal unexpected responses to FTY720 and DMF in experimental autoimmune encephalomyelitis

2016, Behavioural brain research

Nadja Tafferner, Julia Barthelmes, Max Eberle, Thomas Ulshöfer, Marina Henke, Natasja de Bruin, Christoph Mayer, Christian Förch, Gerd Geisslinger, Michael J. Parnham, Susanne Schiffmann

Alpha-methylacyl-CoA racemase deletion has mutually counteracting effects on T-cell responses, associated with unchanged course of EAE

2016, European journal of immunology

Max Eberle, Philipp Ebel, Christoph Mayer, Julia Barthelmes, Nadja Tafferner, Nerea Ferreiros, Thomas Ulshöfer, Marina Henke, Christian Förch, Anika Männer de Bazo, Sabine Grösch, Gerd Geisslinger, Klaus Willecke, Susanne Schiffmann, Johannes A Eble

Exacerbation of experimental autoimmune encephalomyelitis in ceramide synthase 6 knockout mice is associated with enhanced activation/migration of neutrophils

2015, Immunology and cell biology

Christoph Mayer, Anika Männer de Bazo, Christian Förch, Max Eberle, Julia Barthelmes, Nadja Tafferner, Nerea Ferreiros, Thomas Ulshöfer, Marina Henke, Sabine Grösch, Gerd Geisslinger, Klaus Willecke, Susanne Schiffmann

Ceramide synthase6 / C16-ceramides mediate anti-inflammatory effects during the development of EAE and MS possibly by suppressing the migration and by deactivation of neutrophils: a new target for anti-inflammatory therapy in MS?

2015, Multiple Sclerosis Journal

Christoph Mayer, Nadja Tafferner, Julia Barthelmes, Max Eberle, Nerea Ferreiros, Thomas Ulshöfer, Marina Henke, Natasja de Bruin, Gerd Geisslinger, Christian Förch, Michael J. Parnham, Susanne Schiffmann

Different pathophysiological relevance of branched fatty acid metabolism in mice and men: alpha-methylacyl-CoA racemase regulates the T cell response only in experimental autoimmune encephalomyelitis but not in multiple sclerosis

2015, Multiple Sclerosis Journal

Julia Barthelmes, Anika Männer de Bazo, Yael Pewzner-Jung, Katja Schmitz, Christoph Mayer, Christian Förch, Max Eberle, Nadja Tafferner, Nerea Ferreiros, Marina Henke, Gerd Geisslinger, Anthony Futerman, Sabine Grösch, Susanne Schiffmann

Lack of ceramide synthase 2 suppresses the development of experimental autoimmune encephalomyelitis by impairing the migratory capacity of neutrophils

2015, Brain, behavior, and immunity

Max Eberle, Philipp Ebel, Marthe-Susanna Wegner, Julia Barthelmes, Nadja Tafferner, Nerea Ferreiros, Kerstin Birod, Yannick Schreiber, Gurumoorthy Krishnamoorthy, Klaus Willecke, Gerd Geisslinger, Sabine Grösch, Susanne Schiffmann

Regulation of ceramide synthase 6 in a spontaneous experimental autoimmune encephalomyelitis model is sex dependent

2014, Biochemical pharmacology