Prof. Dr. Dr. Gerd Geisslinger

Published Papers

Sorwe Mojtahed Poor, Thomas Ulshöfer, Laureen Gabriel, Marina Henke, Michaela Köhm, Frank Behrens, Gerd Geisslinger, Michael J. Parnham, Harald Burkhardt, Susanne Schiffmann

Immunogenicity assay development and validation for biologic therapy as exemplified by ustekinumab

2019, Clinical & Experimental Immunology

Neda Tarighi, Dominic Menger, Sandra Pierre, Lisa Kornstädt, Dominique Thomas, Nerea Ferreiros, Rolf Nüsing, Gerd Geisslinger, Klaus Scholich

Thromboxane-induced α-CGRP release from peripheral neurons is an essential positive feedback loop in capsaicin-induced neurogenic inflammation.

2018, Journal of Investigative Dermatology

Elsa-Marie Treutlein, Katharina Kern, Andreas Weigert, Neda Tarighi, Claus-Dieter Schuh, Rolf Nüsing, Yannick Schreiber, Nerea Ferreiros, Bernhard Brüne, Gerd Geisslinger, Sandra Pierre, Klaus Scholich

The prostaglandin E2 receptor EP3 controls CC-chemokine ligand 2-mediated neuropathic pain induced by mechanical nerve damage

2018, The Journal of Biological Chemistry

Simone Schierle, Cathrin Flauaus, Pascal Heitel, Sabine Willems, Jurema Schmidt, Astrid Kaiser, Lilia Weizel, Tamara Göbel, Astrid Stefanie Kahnt, Gerd Geisslinger, Dieter Steinhilber, Mario Wurglics, G. Enrico Rovati, Achim Schmidtko, Eugen Proschak, Daniel Merk

Boosting Anti-Inflammatory Potency of Zafirlukast by Designed Polypharmacology

2018, Journal of Medicinal Chemistry

Leonard Blum, Nadja Tafferner, Ilknur Spring, Jennifer Kurz, Natasja de Bruin, Gerd Geisslinger, Michael J. Parnham, Susanne Schiffmann

Dietary phytol reduces clinical symptoms in experimental autoimmune encephalomyelitis (EAE) at least partially by modulating NOX2 expression.

2018, Journal of Molecular Medicine

Andrea E. Vasconez, Patrick Janetzko, James A. Oo, Beatrice Pflüger-Müller, Corina Ratiu, Lunda Gu, Kristian Helin, Gerd Geisslinger, Ingrid Fleming, Katrin Schröder, Christian Fork, Ralf Brandes, Matthias S. Leisegang

The histone demethylase Jarid1b mediates angiotensin II-induced endothelial dysfunction by controlling the 3'UTR of soluble epoxide hydrolase

2018, Acta Physiologica

Hiromi Shiratori, Carmen Feinweber, Sonja Luckhardt, Nadja Wallner, Gerd Geisslinger, Andreas Weigert, Michael J. Parnham

An in vitro test system for compounds that modulate human inflammatory macrophage polarization

2018, European Journal of Pharmacology

Marthe-Susanna Wegner, Nina Schömel, Lisa Gruber, Stephanie Beatrice Örtel, Matti Aleski Kjellberg, Peter Mattjus, Jennifer Kurz, Sandra Trautmann, Bing Peng, Martin Wegner, Manuel Kaulich, Robert Ahrends, Gerd Geisslinger, Sabine Grösch

UDP-glucose ceramide glucosyltransferase activates AKT, promoted proliferation, and doxorubicin resistance in breast cancer cells

2018, Cellular and Molecular Life Sciences

Christian Fork, Andrea E. Vasconez, Patrick Janetzko, Carlo Angioni, Yannick Schreiber, Nerea Ferreiros, Matthias S. Leisegang, Gerd Geisslinger, Dieter Steinhilber, Ralf Brandes

Epigenetic control of microsomal prostaglandin E synthase-1 by HDAC-mediated recruitment of p300

2017, The Journal of Lipid Research

Jessica Roos, Marcus Peters, Isabelle Maucher, Benjamin Kühn, Jasmin Fettel, Nadine Hellmuth, Camilla Brat, Benita Sommer, Anja Urbschat, Matthias Piesche, Anja Vogel, Eugen Proschak, Rene Blöcher, Estel la Buscato, Ann-Kathrin Häfner, Carmela Matrone, Oliver Werz, Juliana Heidler, Ilka Wittig, Carlo Angioni, Gerd Geisslinger, Michael J. Parnham, Kai Zacharowski, Dieter Steinhilber, Thorsten Maier

Drug-Mediated Intracellular Donation of Nitric Oxide Potently Inhibits 5-Lipoxygenase: A Possible Key to Future Antileukotriene Therapy

2017, Antioxidants & Redox Signaling

Katharina Kern, Sandra Pierre, Yannick Schreiber, Carlo Angioni, Dominique Thomas, Nerea Ferreiros, Gerd Geisslinger, Klaus Scholich

CD200 selectively upregulates prostaglandin E2 and D2 synthesis in LPS-treated bone marrow-derived macrophages

2017, Prostaglandins & Other Lipid Mediators

Hiromi Shiratori, Carmen Feinweber, Sonja Luckhardt, Bona Linke, Eduard Resch, Gerd Geisslinger, Andreas Weigert, Michael J. Parnham

THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro

2017, Molecular Immunology

Tanya S King-Himmelreich, Christine V. Möser, Miriam C. Wolters, Julia Schmetzer, Moritz Möller, Yannick Schreiber, Nerea Ferreiros, Gerd Geisslinger, Ellen Niederberger

[EXPRESS] AMP-activated kinase and the endogenous endocannabinoid system might contribute to antinociceptive effects of prolonged moderate caloric restriction in mice

2017, Molecular Pain

Tanya S King-Himmelreich, Christine V. Möser, Miriam C. Wolters, Julia Schmetzer, Yannick Schreiber, Nerea Ferreiros, Otto Quintus Russe, Gerd Geisslinger, Ellen Niederberger

AMPK contributes to aerobic exercise-induced antinociception downstream of endocannabinoids

2017, Neuropharmacology

Stephanie Beatrice Örtel, Klaus Scholich, Andreas Weigert, Dominique Thomas, Julia Schmetzer, Sandra Trautmann, Marthe-Susanna Wegner, Heinfried H. Radeke, Natalie Filman, Bernhard Brüne, Gerd Geisslinger, Irmgard Tegeder, Sabine Grösch

Ceramide synthase 2 deficiency aggravates AOM-DSS-induced colitis in mice: role of colon barrier integrity

2017, Cellular and Molecular Life Sciences

Katrin Olbrich, Lara Costard, Christine V. Möser, Katharina Syhr, Tanya S King-Himmelreich, Miriam C. Wolters, Achim Schmidtko, Gerd Geisslinger, Ellen Niederberger

Cleavage of SNAP-25 ameliorates cancer pain in a mouse model of melanoma

2017, European Journal of Pain

Sebastian Zinn, Marco Sisignano, Katharina Kern, Sandra Pierre, Sorin Tunaru, Holger Jordan, Jing Suo, Elsa-Marie Treutlein, Carlo Angioni, Nerea Ferreiros, Andreas Leffler, Natasja de Bruin, Stefan Offermanns, Gerd Geisslinger, Klaus Scholich

The leukotriene B4 receptors BLT1 and BLT2 form an antagonistic sensitizing system in peripheral sensory neurons

2017, Journal Of Biological Chemistry

Hiromi Shiratori, Carmen Feinweber, Claudia Knothe, Jörn Lötsch, Dominique Thomas, Gerd Geisslinger, Michael J. Parnham, Eduard Resch

High-Throughput Analysis of Global DNA Methylation Using Methyl-Sensitive Digestion

2016, PloS one

Marco Sisignano, Carlo Angioni, Chul-Kyu Park, Sascha Meyer Dos Santos, Holger Jordan, Maria Kuzikov, Di Liu, Sebastian Zinn, Stephan Hohmann, Yannick Schreiber, Béla Zimmer, Mike Schmidt, Ruirui Lu, Jing Suo, Dong-Dong Zhang, Stephan M. G. Schäfer, Martine Hofmann, Ajay S. Yekkirala, Natasja de Bruin, Michael J. Parnham, Clifford J. Woolf, Ru-Rong Ji, Klaus Scholich, Gerd Geisslinger

Targeting CYP2J to reduce paclitaxel-induced peripheral neuropathic pain

2016, Proceedings of the National Academy of Sciences

Katja Zschiebsch, Caroline Fischer, Geethanjali Pickert, Annett Haussler, Heinfried H. Radeke, Sabine Grösch, Nerea Ferreiros, Gerd Geisslinger, Ernst Werner, Irmgard Tegeder

Tetrahydrobiopterin Attenuates DSS-evoked Colitis in Mice by Rebalancing Redox and Lipid Signalling

2016, Journal of Crohn's & colitis

Katharina Syhr, Sebastian Zinn, Gerd Geisslinger

Arzneimittelinteraktionen – „App” to date

2016, Aktuelle Neurologie

Tanya S King-Himmelreich, Stefanie Schramm, Miriam C. Wolters, Julia Schmetzer, Christine V. Möser, Claudia Knothe, Eduard Resch, Johannes Peil, Gerd Geisslinger, Ellen Niederberger

The impact of endurance exercise on global and AMPK gene-specific DNA methylation

2016, Biochemical and biophysical research communications

Claudia Knothe, Hiromi Shiratori, Eduard Resch, Alfred Ultsch, Gerd Geisslinger, Alexandra Doehring, Jörn Lötsch

Disagreement between two common biomarkers of global DNA methylation

2016, Clinical Epigenetics Society

Christine V. Möser, Markus Meissner, Kathrin Laarmann, Katrin Olbrich, Tanya S King-Himmelreich, Miriam C. Wolters, Gerd Geisslinger, Ellen Niederberger

The protein kinase IKKepsilon contributes to tumour growth and tumour pain in a melanoma model

2016, Biochemical Pharmacology

Ivana Josipovic Josipovic, Christian Fork, Jens Preussner, Kim-Kristin Prior, Dijana Iloska, Andrea E. Vasconez, Sandra Labocha, Carlo Angioni, Dominique Thomas, Nerea Ferreiros, Mario Looso, Soni S. Pullamsetti, Gerd Geisslinger, Dieter Steinhilber, Ralf Brandes, Matthias S. Leisegang

PAFAH1B1 and the lncRNA NONHSAT073641 maintain an angiogenic phenotype in human endothelial cells

2016, Acta Physiologica

Karin Meirer, Daniel Glatzel, Simon Kretschmer, Sandra K Wittmann, Markus Hartmann, Rene Blöcher, Carlo Angioni, Gerd Geisslinger, Dieter Steinhilber, Bettina Hofmann, Robert Fürst, Eugen Proschak

Design, Synthesis and Cellular Characterization of a Dual Inhibitor of 5-Lipoxygenase and Soluble Epoxide Hydrolase

2016, Molecules

Julia Barthelmes, Nadja Tafferner, Jennifer Kurz, Natasja de Bruin, Michael J. Parnham, Gerd Geisslinger, Susanne Schiffmann

Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues

2016, Journal of visualized experiments

Jörn Lötsch, Violeta Dimova, Alfred Ultsch, Isabel Lieb, Michael Zimmermann, Gerd Geisslinger, Bruno Oertel

A small yet comprehensive subset of human experimental pain models emerging from correlation analysis with a clinical quantitative sensory testing protocol in healthy subjects

2016, European Journal of Pain

Natasja de Bruin, Katja Schmitz, Susanne Schiffmann, Nadja Tafferner, Mike Schmidt, Holger Jordan, Annett Haussler, Irmgard Tegeder, Gerd Geisslinger, Michael J. Parnham

Multiple rodent models and behavioral measures reveal unexpected responses to FTY720 and DMF in experimental autoimmune encephalomyelitis

2016, Behavioural brain research

Claudia Knothe, Bruno Oertel, Alfred Ultsch, Mattias Kettner, Peter Harald Schmidt, Cora Wunder, Stefan W. Toennes, Gerd Geisslinger, Jörn Lötsch

Pharmacoepigenetics of the role of DNA methylation in mu-opioid receptor expression in different human brain regions

2016, Epigenomics

Simon Kretschmer, Stefano Woltersdorf, Dominik Vogt, Felix F. Lillich, Michael Rühl, Michael Karas, Isabelle Maucher, Jessica Roos, Ann-Kathrin Häfner, Astrid Kaiser, Mario Wurglics, Manfred Schubert-Zsilavecz, Carlo Angioni, Gerd Geisslinger, Holger Stark, Dieter Steinhilber, Bettina Hofmann

Characterization of the molecular mechanism of 5-lipoxygenase inhibition by 2-aminothiazoles

2016, Biochemical Pharmacology

Isabelle Maucher, Michael Rühl, Simon Kretschmer, Bettina Hofmann, Benjamin Kühn, Jasmin Fettel, Anja Vogel, Karsten T. Flügel, Georg Manolikakes, Nadine Hellmuth, Ann-Kathrin Häfner, Vahid Golghalyani, Ann-Katrin Ball, Matthias Piesche, Carmela Matrone, Gerd Geisslinger, Michael J. Parnham, Michael Karas, Dieter Steinhilber, Jessica Roos, Thorsten Maier

Michael acceptor containing drugs are a novel class of 5-lipoxygenase inhibitor targeting the surface cysteines C416 and C418

2016, Biochemical Pharmacology

Nadja Tafferner, Julia Barthelmes, Max Eberle, Thomas Ulshöfer, Marina Henke, Natasja de Bruin, Christoph Mayer, Christian Förch, Gerd Geisslinger, Michael J. Parnham, Susanne Schiffmann

Alpha-methylacyl-CoA racemase deletion has mutually counteracting effects on T-cell responses, associated with unchanged course of EAE

2016, European journal of immunology

Rene Blöcher, Christina Lamers, Sandra K Wittmann, Daniel Merk, Markus Hartmann, Lilia Weizel, Olaf Diehl, Astrid Brüggerhoff, Marcel Boss, Astrid Kaiser, Tim Schader, Tamara Göbel, Manuel Grundmann, Carlo Angioni, Jan Heering, Gerd Geisslinger, Mario Wurglics, Evi Kostenis, Bernhard Brüne, Dieter Steinhilber, Manfred Schubert-Zsilavecz, Astrid Stefanie Kahnt, Eugen Proschak

N-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators

2016, Journal of medicinal chemistry

Christoph Lehmann, Julia Homann, Ann-Katrin Ball, Rene Blöcher, Thea K Kleinschmidt, Devaraj Basavarajappa, Nerea Ferreiros, Ann-Kathrin Häfner, Olof Radmark, Jesper Z Haeggstrom, Gerd Geisslinger, Michael J. Parnham, Dieter Steinhilber, Astrid Stefanie Kahnt

Lipoxin and resolvin biosynthesis is dependent on 5-lipoxygenase activating protein

2015, FASEB Journal

Tanya S King-Himmelreich, Christine V. Möser, Miriam C. Wolters, Katrin Olbrich, Gerd Geisslinger, Ellen Niederberger

Age-Dependent Changes in the Inflammatory Nociceptive Behavior of Mice

2015, International journal of molecular sciences

Max Eberle, Philipp Ebel, Christoph Mayer, Julia Barthelmes, Nadja Tafferner, Nerea Ferreiros, Thomas Ulshöfer, Marina Henke, Christian Förch, Anika Männer de Bazo, Sabine Grösch, Gerd Geisslinger, Klaus Willecke, Susanne Schiffmann, Johannes A Eble

Exacerbation of experimental autoimmune encephalomyelitis in ceramide synthase 6 knockout mice is associated with enhanced activation/migration of neutrophils

2015, Immunology and cell biology

Katharina Syhr, Meike Boosen, Stephan Hohmann, Sebastian Longen, Yvette Kohler, Josef Pfeilschifter, Karl-Friedrich Beck, Gerd Geisslinger, Achim Schmidtko, Wiebke Kallenborn-Gerhardt

The H2S-producing enzyme CSE is dispensable for the processing of inflammatory and neuropathic pain

2015, Brain research

Katharina Syhr, Bruno Oertel, Gerd Geisslinger

Drug interactions in pain therapy

2015, Schmerz

Tanya S King-Himmelreich, Otto Quintus Russe, Christine V. Möser, Nerea Ferreiros, Katharina Kynast, Claudia Knothe, Katrin Olbrich, Gerd Geisslinger

AMP-activated protein kinase is activated by non-steroidal anti-inflammatory drugs

2015, European journal of pharmacology

Christine V. Möser, Heike Stephan, Katharina Altenrath, Katharina Kynast, Otto Quintus Russe, Katrin Olbrich, Gerd Geisslinger, Ellen Niederberger

TANK-binding kinase 1 (TBK1) modulates inflammatory hyperalgesia by regulating MAP kinases and NF-kappaB dependent genes

2015, Journal of neuroinflammation

Christoph Mayer, Nadja Tafferner, Julia Barthelmes, Max Eberle, Nerea Ferreiros, Thomas Ulshöfer, Marina Henke, Natasja de Bruin, Gerd Geisslinger, Christian Förch, Michael J. Parnham, Susanne Schiffmann

Different pathophysiological relevance of branched fatty acid metabolism in mice and men: alpha-methylacyl-CoA racemase regulates the T cell response only in experimental autoimmune encephalomyelitis but not in multiple sclerosis

2015, Multiple Sclerosis Journal

Christoph Mayer, Anika Männer de Bazo, Christian Förch, Max Eberle, Julia Barthelmes, Nadja Tafferner, Nerea Ferreiros, Thomas Ulshöfer, Marina Henke, Sabine Grösch, Gerd Geisslinger, Klaus Willecke, Susanne Schiffmann

Ceramide synthase6 / C16-ceramides mediate anti-inflammatory effects during the development of EAE and MS possibly by suppressing the migration and by deactivation of neutrophils: a new target for anti-inflammatory therapy in MS?

2015, Multiple Sclerosis Journal

Julia Barthelmes, Anika Männer de Bazo, Yael Pewzner-Jung, Katja Schmitz, Christoph Mayer, Christian Förch, Max Eberle, Nadja Tafferner, Nerea Ferreiros, Marina Henke, Gerd Geisslinger, Anthony Futerman, Sabine Grösch, Susanne Schiffmann

Lack of ceramide synthase 2 suppresses the development of experimental autoimmune encephalomyelitis by impairing the migratory capacity of neutrophils

2015, Brain, behavior, and immunity

Catherine Olesch, Weixiao Sha, Carlo Angioni, Lisa Sha, Elias Acaf, Paola Patrignani, Per-Johan Jakobsson, Heinfried H. Radeke, Sabine Grösch, Gerd Geisslinger, Andreas von Knethen, Andreas Weigert, Bernhard Brüne

MPGES-1-derived PGE2 suppresses CD80 expression on tumor-associated phagocytes to inhibit anti-tumor immune responses in breast cancer

2015, Oncotarget

Jörn Lötsch, Violeta Dimova, Hanneke Hermens, Michael Zimmermann, Gerd Geisslinger, Bruno Oertel, Alfred Ultsch

Pattern of neuropathic pain induced by topical capsaicin application in healthy subjects

2015, Pain

Max Eberle, Philipp Ebel, Marthe-Susanna Wegner, Julia Barthelmes, Nadja Tafferner, Nerea Ferreiros, Kerstin Birod, Yannick Schreiber, Gurumoorthy Krishnamoorthy, Klaus Willecke, Gerd Geisslinger, Sabine Grösch, Susanne Schiffmann

Regulation of ceramide synthase 6 in a spontaneous experimental autoimmune encephalomyelitis model is sex dependent

2014, Biochemical pharmacology

Jana Lorenz, Wiebke Kallenborn-Gerhardt, Ruirui Lu, Katharina Syhr, Philip Eaton, Gerd Geisslinger, Achim Schmidtko

Oxidant-induced activation of cGMP-dependent protein kinase Iα mediates neuropathic pain after peripheral nerve injury

2014, Antioxid Redox Signal

Wiebke Kallenborn-Gerhardt, Stephan Hohmann, Katharina Syhr, Katrin Schröder, Marco Sisignano, Andreas Weigert, Jana Lorenz, Ruirui Lu, Bernhard Brüne, Ralf Brandes, Gerd Geisslinger, Achim Schmidtko

Nox2-dependent signaling between macrophages and sensory neurons contributes to neuropathic pain hypersensitivity

2014, Pain

Katharina Syhr, Wiebke Kallenborn-Gerhardt, Ruirui Lu, Katrin Olbrich, Katja Schmitz, Julia Barthelmes, Nerea Ferreiros, Gerd Geisslinger, Ellen Niederberger, Achim Schmidtko

Lack of effect of a P2Y6 receptor antagonist on neuropathic pain behavior in mice

2014, harmacology, biochemistry, and behavior

Katja Schmitz, Natasja de Bruin, Philipp Bishay, Julia Barthelmes, Annett Haussler, Christine Altmann, Nerea Ferreiros, Jörn Lötsch, Alfred Ultsch, Michael J. Parnham, Gerd Geisslinger, Irmgard Tegeder

R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice

2014, EMBO molecular medicine

Khader Awwad, Svenja Steinbrink, Timo Frömel, Nicole Mangels, Johann Isaak, Ann-Kathrin Häfner, Jessica Roos, Bettina Hofmann, Heinrich Heide, Gerd Geisslinger, Dieter Steinhilber, Bruce Freeman, Thorsten Maier, Ingrid Fleming

Electrophilic Fatty Acid Species Inhibit 5-Lipoxygenase and Attenuate Sepsis-Induced Pulmonary Inflammation

2014, Antioxidants & redox signaling

Julia Homann, Christoph Lehmann, Astrid Stefanie Kahnt, Dieter Steinhilber, Michael J. Parnham, Gerd Geisslinger, Nerea Ferreiros

Chiral chromatography-tandem mass spectrometry applied to the determination of pro-resolving lipid mediators

2014, Journal of Chromatography A

Otto Quintus Russe, Christine V. Möser, Katharina Kynast, Tanya S King-Himmelreich, Katrin Olbrich, Sabine Grösch, Gerd Geisslinger, Ellen Niederberger

LPS inhibits caspase 3-dependent apoptosis in RAW264.7 macrophages induced by the AMPK activator AICAR

2014, Biochemical and biophysical research communications

Sebastian Sailler, Katja Schmitz, Elke Jäger, Nerea Ferreiros, Sabine Wicker, Katja Zschiebsch, Geethanjali Pickert, Gerd Geisslinger, Carmen Walter, Irmgard Tegeder, Jörn Lötsch

Regulation of circulating endocannabinoids associated with cancer and metastasis in mice and humans

2014, Oncoscience

Michael Schütz, Bruno Oertel, Dirk Heimann, Alexandra Doehring, Carmen Walter, Violeta Dimova, Gerd Geisslinger, Jörn Lötsch

Consequences of a human TRPA1 genetic variant on the perception of nociceptive and olfactory stimuli

2014, PLoS One

Susanne Schiffmann, Andreas Weigert, Julia Barthelmes, Max Eberle, Kerstin Birod, Annett Haussler, Nerea Ferreiros, Yannick Schreiber, Manuel Grez, Weichand Benjamin Benjamin, Bernhard Brüne, Waltraud Pfeilschifter, Rolf Nüsing, Ellen Niederberger, Sabine Grösch, Klaus Scholich, Gerd Geisslinger

PGE2/EP4 signaling in peripheral immune cells promotes development of experimental autoimmune encephalomyelitis

2014, Biochemical pharmacology

Susanne Schiffmann, Kerstin Birod, Julia Barthelmes, Max Eberle, Marthe-Susanna Wegner, Ruth Wanger, Daniela Hartmann, Nerea Ferreiros, Gerd Geisslinger, Sabine Grösch

Ceramide metabolism in mouse tissue

2013, The international journal of biochemistry & cell biology

Astrid Stefanie Kahnt, Florian Rörsch, Olaf Diehl, Bettina Hofmann, Christoph Lehmann, Svenja Steinbrink, Carlo Angioni, Gerd Geisslinger, Sabine Grösch, Thorsten Maier

Cysteinyl leukotriene-receptor-1 antagonists interfere with PGE synthesis by inhibiting mPGES-1 activity

2013, Biochemical pharmacology

Wiebke Kallenborn-Gerhardt, Ruirui Lu, Katharina Syhr, Juliana Heidler, Harald von Melchner, Gerd Geisslinger, Thorsten Bangsow, Achim Schmidtko

Antioxidant activity of Sestrin 2 controls neuropathic pain after peripheral nerve injury

2013, Antioxidants & redox signaling

Susanne Schiffmann, Nerea Ferreiros, Kerstin Birod, Max Eberle, Yannick Schreiber, Waltraud Pfeilschifter, Ulf Ziemann, Sandra Pierre, Klaus Scholich, Sabine Grösch, Gerd Geisslinger

Ceramide synthase 6 plays a critical role in the development of experimental autoimmune encephalomyelitis

2012, The Journal of Immunology